Journal: Journal of Cannabis Research

Article Title: Design, synthesis, and biological profiling of fluorinated cannabidiol and cannabigerol derivatives as promising therapeutic agents

doi: 10.1186/s42238-026-00403-1

Figure Lengend Snippet: Inhibitory effects of CBD ( A ) and CBG derivatives ( B ) on human renal cancer cells. A-498 and CAKI-2 cell lines plated with 6 × 10 3 density were treated with 10, 30 and 60 µM of the examined compounds, respectively, and fluorescence intensities of living cells were measured to determine the cytotxic effect of the compounds. The intensity of treated samples was normalized to the untreated control samples. Value of 0.05 was set as the threshold for statistical significance. The figure represents mean ± SD

Article Snippet: Human renal carcinoma cell lines, A-498 and CAKI-2 obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA) were cultured in Iscove’s Modified Dulbecco’s Medium (IMDM) supplemented with 10% Fetal Bovine Serum (FBS) and antibiotics (100 U/ml penicillin and 100 μg/ml streptomycin) and maintained at 37 °C in a humidified atmosphere under 5% CO 2 /95% air.

Techniques: Fluorescence, Control